First of all, this is a big update in terms of affected API. Many functions have been renamed/moved/updated. All functionality is still available, but any code that uses rustyms needs some manual updates.
Here is a shortlist of the most important things that have changed, if you want a full list check out [cargo-public-api](https://github.com/enselic/cargo-public-api):
* Alignment is more robust and allows for more settings, either global and different matrices are notable additions
* All germline sequences from IMGT are now included as well as methods of iterating over them
* Many more things now support Eq+Ord+Hash thanks to use of the ordered-float crate
* Many tuple results have been refactored to be small structs with named fields
* Amino acids now have different property classes defined
* The functions have been updated to handle ambiguous amino acids throughout so using B/Z now will never crash