[View detailed changelog](https://github.com/neuropoly/axondeepseg/compare/v3.3.0...v4.0.0)
**NOTICE**
- Due to the change in implementations on an upgraded dependency (skimage v0.14.2 -> v0.18.3), the morphometrics values "solidity" and "orientation" differ from values produced by AxonDeepSeg v3.x. "solidity" values produced can vary slightly due to numerical precision in algorithmic changes in skimage (on the order of 1%), a the convention for "orientation" changed from "rc" to "xy", leading to a difference in value by pi/2. See this issue for more details: https://github.com/neuropoly/axondeepseg/issues/589
**BUG**
- Fix NaNs not appearing when generating morphometrics with the GUI [View pull request](https://github.com/neuropoly/axondeepseg/pull/592)
**FEATURE**
- Integrate IVADOMED into project [View pull request](https://github.com/neuropoly/axondeepseg/pull/547)
- Changed all instances of imageio_imread by ads_utils.imread [View pull request](https://github.com/neuropoly/axondeepseg/pull/5927)
**INSTALLATION**
- Added Mac M1 compatibility [View pull request](https://github.com/neuropoly/axondeepseg/pull/547)