**Major upgrades**
Add function `bigfish.detection.compute_snr` to compute signal-to-noise ratio (c26195e7bb774077ed2394a04cfffb3cbc0f4ce6, b3a20783dbb448460e427e5828a38fb6792f2a49, 44d7b367a9305048a56cb6255bccd3bea03893f7, b753784d7d29bd6dde0a96cf4789a65bb1a4ef22, fabb7e2653de183c3b0dd9e168ddde58c0563a2e, e367a2f0e25a0e34b82714b7fb562b05549b9e53, ba8806aa232b3b0d95257af413c0879d165b13f6)
Add sphinx documentation (751190e44e092a9f9466ff19bfd1fce79876039a, c77a08c0430b47bb403a952f823ca17c60e8e168, e26aa28aab4821cb9752036d3ca5b073be760b95, 31af14c0675006523e3c66bc80030a36c5091c49, cfbc90e0182fb24e4eacd5cae36fb0dcff692827, ddd131968357ca23cbed974a82762026911e1fd8, 86e21adb70d5f663e6107f9d31529da7c07017ac, 22cbf0a7b40d6b4c71577cf291ded012fecbaaea, 7520e0d55f2ad9265fd4dffd87bdf358ebf6a456, aaa0d6a590ec85af1c0d5170bc3e3c3c7d6969ab, 0f46ba10153db7074ffdda01ad5ae1947d3ccd1a, 8ab1e39d646e404585e94ce147e8c4f1e66dba36, 43b60a6e448d50659ee1274d5d466fc568137638, 943f53762c3d0179fca4984f6cf156701e128113)
Refactor and reword `bigfish.detection` (d219373c0c0ab2670c21eac2ec33ab39157d3d2e, fa0df4fdd10656e6c87371c22fefa4fef43de3df)
Add deep learning models to segment nuclei and cells (a901bd8f0d91641313be0aeb72bfa7d24ee0207a, 9ebf35ef5c182355a757a46ec5c81b49ab1c1233, 4dfc43196fa5ecb2d02dc2e407427f83a7623372, efc51ffb4719378b9ce189f6d7ec709a9ff5d448, 37fb620bfabf57a2c96bc22a6c0f4c124269795d, fac4a75c54fb4628b5e37b487b23fc90a521f3ba)
Add function `bigfish.plot. plot_elbow` to plot the elbow curve (3e47346322aff05346e793c4fa0829ddad50b687, 76ec30604a4014a6bfa06d1a6f107a5c32fd86f9)
Add function `bigfish.detection.fit_subpixel` to perform subpixel spot detection (ddab58446bc4ab2726a9426d53da0338cafa90fb)
**Minor upgrades**
Move `get_sigma` and `get_radius` in `bigfish.stack` (1827749eded9341d1e5563b94046b0b859b7d6fb)
Remove outdated functions and modules (2607f36a8f007dbc41421d2b1296ac55e385a06b)
Make `bigfish.stack.mean_filter` faster (13b4ce8b8aabee0cc783161c61f96077fb58fc7b)
Allow float image for `bigfish.stack.mean_filter` (6ad1eecce45609783af94f0b96545872ef098288)
Refactor functions for focus projection and measure (0e23bfec08df438689d38c530aaea718946c2442)
Allow float spot coordinates for `bigfish.plot.plot_detection` (6613f1105c8d88b1c0745283d911b24cb45a08ee)
Add parameter in `bigfish.detection.decompose_dense` to manage the denoising filter (4766885e1de26d09d2c8c58f3dd9427924c87173)
Remove original version of focus projection (b9d1afcc881f68a3160ba76a2c23ec7bed5bd836)
Add warning when no spot is detected (5ee4e7a2dab52f94870358b1d1e99a141d633c5f)
Update `setup.py` (6fd8e845bb513fed354a98e916127aa43eeef3ab, 9a9cf2bef0ae4c74344b49deba39c52e9e154eb2)
Add functions to count segmented instance and compute their diameter (8847fb4b281ce84a9f898ddc0701fd8106b3d0f3)
Add function `bigfish.stack.augment_2d_function` to randomly return an image augmentation transformation (eea2c3557fde80b83a311fe087ccb8a998597250)
Change default frame size in `bigfish.plot` (e9596e3080b3652a5befc509697bc0d4befa3c23)
Add function `bigfish.plot.plot_segmentation_diff` to compare segmented instance with their ground truth (2545457ec80878ed3bd6b464b4f333b0fb505c21, 0f18d9bf62838962054955341fbe74f4e53449b2)
Improve postprocessing functions in `bigfish.segmentation` and nucleus-cell matching (1298f1bdfc8e353bba106ac32c751afdb9e916df, dcd9c1c43a0c70040f3c38416ec21572ed095d4c)
Add function `bigfish.stack.augment_8_times` to apply every augmentation transformation to an image(e3932ca954257539a6b7d7ef06fedbbfeb21a35d, 6795748a31801404663ffb97692005a9b1cad614)
Make some functions public to be imported from external packages (e1c104e690fd15a9ee1605c27353bae4a2f68e2d, f544f2e49002d99a4a1509e565c9fd19b5f473ff)
Update loader functions to get new images for example (611569419bc65e82b0870fad5830b3c144395a50)
Remove a former module used for pattern classification (2b8ebaa611170b62be1db0b2b6034a5faa43dcc6)
Update README (be21078d1fe2cb3a28e473268bc1fc5deff3bc40)
Update `requirement_dev.txt` (39faf85def17b8dbcec23dedda1a254a6efc3df7)
**Bug fixes**
Fix bug with float voxel_size in `bigfish.detection` (b9776d54690e36a2d689c073012789c2fcb99e68)
Fix bug in `bigfish.plot.plot_images` (b3a47d3afbca461b7d1db83db36b31e7fd2a57f2)