Gmx-mmpbsa

Latest version: v1.6.4

Safety actively analyzes 693883 Python packages for vulnerabilities to keep your Python projects secure.

Scan your dependencies

Page 2 of 5

1.5.6

Fix

gmx_MMPBSA

- Inconsistent decomposition output (246, 248)
- IE and C2 entropies calculation fail when rewrite-output (253)
- Delta Delta Entropies' values are incorrect (257)
- Loading binary file fails when alanine scanning is performed (258)

gmx_MMPBSA_ana

- Mutant-Normal data is not computed or displayed (254)
- Inconsistent energy values in PyMol visualization (255)

Changes

gmx_MMPBSA

- Re-implementation of compact binary output file (249)

1.5.5

Additions

gmx_MMPBSA

- Improved the API (209)
- Added a new method to get the Enthalpy
- Added a new method to get the Entropy
- Added a new method to get the Binding
- Added a new method to get the Decomposition energy
- Added a new method to get the gmx_MMPBSA_ana data

gmx_MMPBSA_ana
- Added multiprocessing and multithreading (209)
- Wait indicator
- Added Error line cap size
- Systems, subsystems and component selection options
- Added threshold to remove energetic terms or residues
- Correlation (137)
- Normal correlation using ΔG
- Mutant correlation using ΔΔG
- Energy values table
- Interactive systems selection and Experimental Ki editor
- New regression plot with bivariate and univariate graphs
- Chart options panel
- General options
- Regression options
- Scatter
- Distribution

Documentation
- News section
- Animated command-line code block with terminal
- Added versioning
- Added installation using *.yml configuration file (221)
- Added a new tutorial for correlation analysis (194)

Fix
gmx_MMPBSA_ana
- Close gmx_MMPBSA_ana properly when the selection dialog is rejected
- Compatibility with previous versions (`< v1.5.2`)
- Added several tooltips
- Improved general performance. See the [benchmark](analyzer.mdfast-like-a-rocket) (209, 230, 243)
- Improved the reading of output files and optimized data storage. (228)
- Eliminated the recalculation of IE and C2 entropies before opening the GUI. Now read from outputs files
- Optimized data storage and access to subsets in panda's Dataframes
- Now file processing and graphics generation does not freeze the GUI.
- Removed redundant steps and data
- Removed line graphs for components in the per-wise decomposition schema
- Data access, processing, and storage are done in the API.
- Added the option to temporarily store data on the hard disk instead of memory
- Removed several pop-up windows
- Decreased RAM consumption

- Removed H5 support
- Invalid periodicity in the prmtop (211)
- Buffer saturation (213)


Changes
gmx_MMPBSA
- Improved IE and C2 calculation

gmx_MMPBSA_ana

- Change the IE representation
- Removed summary widget
- Now the bar plot data contain the Average, SD, and SEM instead of all frames
- Chart Options
- Error line color
- Error line representation (SD or SEM)

- Restructured the init (system selection) dialog
- Improved energy and decomposition options selection
- Improved the correlation options
- Added a new section for performance configuration
- Added RAM consumption estimator
- Improved the systems' tree representation and edition options


gmx_MMPBSA_test
- The examples folder moved up to the root directory

1.5.2

Additions

`gmx_MMPBSA`

- ALPB (Analytical Linearized Poisson-Boltzmann) approximation (170)
- PC+ correction in 3D-RISM (187)
- Warning when using `-deo` option without &decomp namelist in the input file (191)

`gmx_MMPBSA_ana`

- Tooltips for different options (151)

Fix

`gmx_MMPBSA_ana`

- Chart options (185)

Changes

`gmx_MMPBSA`

- 3D-RISM calculated with sander instead of rism3d.snglpnt (153)

`Documentation`

- Update 3D-RISM doc (190)

1.5.1

Additions

`gmx_MMPBSA`
- Add new variables for QM/MM calculations (171)
- Improvement of "print_res" function for &decomp and QM (150)
- Support for OPLS force field (160)
- New precalculated .xvv files for 3D-RISM

`gmx_MMPBSA_ana`
- Support for PyQt6

`Documentation`
- gmx_MMPBSA_ana documentation (v1.5.0) (152)
- [Tutorial for psf_dcd files](https://valdes-tresanco-ms.github.io/gmx_MMPBSA/examples/#support-for-psf_dcd-files)
- [Tutorial for OPLS ff files](https://valdes-tresanco-ms.github.io/gmx_MMPBSA/examples/#oplsff-support)

Fixes
`gmx_MMPBSA`
- Add ERROR when ligand.mol2 defined and no gaff or gaff2 in forcefields variable (175)
- [fixed incorrect path search when the gmx_path is defined](https://github.com/Valdes-Tresanco-MS/gmx_MMPBSA/commit/67bd79a265145ba8f35c117aacfc1d5d9d6aa627)
- [Fixed error when no ions are included in the groups defined](https://github.com/Valdes-Tresanco-MS/gmx_MMPBSA/commit/e99946902118cd80c2cae5393ff5febbbfb85550)

`gmx_MMPBSA_ana`
- Remove empty terms issue (179)
- [fixed chart title for decomposition](https://github.com/Valdes-Tresanco-MS/gmx_MMPBSA/commit/d31c1a32a01c9941ef39940d0b8a9b59da411b31)

1.5.0.3

What's Changed
* Improved nmode and sd in the output in https://github.com/Valdes-Tresanco-MS/gmx_MMPBSA/pull/169
* Improved autocompletion script
* Updated 3D-RISM, NMODE, Alascan, Decomp, and Linear/Non-Linear PB solver tutorials


**Full Changelog**: https://github.com/Valdes-Tresanco-MS/gmx_MMPBSA/compare/v1.5.0.2...v1.5.0.3

1.5.0.2

What's Changed
* Improve topology cleanup https://github.com/Valdes-Tresanco-MS/gmx_MMPBSA/pull/165


**Full Changelog**: https://github.com/Valdes-Tresanco-MS/gmx_MMPBSA/compare/v1.5.0.1...v1.5.0.2

Page 2 of 5

© 2025 Safety CLI Cybersecurity Inc. All Rights Reserved.