Immunedb

Latest version: v0.29.11

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0.18.0

* The package has been renamed from AIRRDB to ImmuneDB.
* Tests now check for the presence of a local-alignment binary.
* SciPy has been removed as a dependency and a custom hypergeom function has
been included.

0.17.0

* The package has been renamed from SLDB to AIRRDB.
* J-gene offsets are now set to human values by default.
* Local alignment has been updated and should properly work for most sequences.

0.16.2

* Selection pressure can now be calculated for mutations happening exactly a
specified number of times.
* Clonal overlap calculations are now faster.
* A `sldb_sql` command has been added to ease direct interface with MySQL.
* API call for clonal overlap now properly pages.
* Improved error handling in lineage construction.
* Docker compose is now used to separate the different AIRRDB components.

0.16.1

* J-genes are now properly assigned.

0.16.0

* Alleles are no longer annotated.
* Sequences can be optionally trimmed during identification or importing.
* Sequences with stop codons can optionally be excluded from lineages.
* Sequences are now properly assigned to clones regardless of CDR3 length.
* Sequences with ambiguous bases in their J-genes are now properly identified.
* V- and J-gene tie code has been consolidated.
* Total clone copy number is now properly calculated for statistics.
* Sequences with ambiguous CDR3s are now properly added to clones.
* V-ties for locally-aligned sequences are now properly annotated.
* Mutation rate for each sample is now stored in the underlying database.
* Lineage node copy numbers are now correct for collapsed sequences
* Clone overlap queries are now much faster.

0.15.0

* Local alignment now uses external libraries.
* Insertions and deletions are now included in sequence records
* A Dockerfile is now available for AIRRDB.

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