- Major changes. Scoary now implements the pairwise comparisons algorithm to account for population structure.
- Scoary now imports 4 classes: Matrix, QuadTree, PhyloTree and Tip. They two former are used for storing pairwise distances between isolates, and the two latter are used for the pairwise comparisons algorithm. Scoary_methods contain some new functions and most of the old ones have been altered to allow the pairwise comparisons implementation. However, there are no changes to how Scoary calculates the previously implemented statistics.
- There should now be a significant speed increase, as Scoary now stores Fisher's exact test p-values rather than re-calculating for every gene. Previously, a new calculation was made for every gene, even when the 2x2 table was identical.