Biolink-model

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Fixed typo in 'treatement' -> 'treatment'
Removed UniProtKB from Gene class ID prefix list
Changed contact email from Deepak->Sierra

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BiolinkML->LinkML name change support

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Updated identifiers to canonical forms
Added predicates for increase/decrease expression predicates, opposite of predicate, generalized
domain for treats and transcription/translation predicates
Domain/range changes for 'interacts with' predicate
Add owlstart enumerations for logical interpretations
Fixed part of the documentation bug for 'types' (linkml changes in progress), added environmental context
as another doc fix

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Corrected NCBIGene prefix (from NCBIGENE)
Reverted ontology taxon parent to named thing

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Corrected the exact mappings for CTD positive and negative correlation predicates
Refined the modeling of ontology class as a mixin
Removed slot_uri for 'subclass of' predicate
Moved CTD:therapeutic from 'exacerbates' to 'ameliorates'
Fixed range for category slot in the 'association' class
Cleaned up prefixes for INO and HANCESTRO
Removed commas in class and predicate names

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Fixed mapping for CTD
Added catalyst qualifier slot
Updated guidelines with examples
Extended the model to represent spatiotemporal exposures, outcomes, and cohorts
Added 'pathological process' class
Predicates that are symmetric are defined explicitly
Added a new 'activity' class
Fixed mixin hierarchy of transcript and RNA products
Extended the model to represent entities from MODs
Reorganized the chemical substance hierarchy
Added a class to represent siRNA
Improved the organization of 'pathological process'
Added more prefixes for various classes
Changed category slot required for 'named thing' and optional for 'association'