What's Changed
Add two kinetic models for binding reactions
This commits adds new kinetic models for two binding mechanisms.
- '3st_induced_fit' models a binding event followed by a change of
conformation. The binding event parameters are a dissociation
constant "KD_AB" and an off-rate "KOFF_AB". The change of
conformation is modeled using two kinetic rate constants: "KBC" and
"KCB".
- '3st_double_binding" models a fork model where a protein can bind
its partner in two different ways. The parameters of the binding
event AB (AC) are a dissociation constant "KD_AB" ("KD_AC") and an
off-rate "KOFF_AB" ("KOFF_AC").
The two models require two parameters, "p_total" and "l_total", to be
specified in the conditions.
Add a 15N SQ shift experiment
* Bump loader-utils from 2.0.2 to 2.0.4 in /website by dependabot in https://github.com/gbouvignies/ChemEx/pull/77
* Bump json5 from 2.2.1 to 2.2.3 in /website by dependabot in https://github.com/gbouvignies/ChemEx/pull/79
* Bump minimatch, recursive-readdir and serve-handler in /website by dependabot in https://github.com/gbouvignies/ChemEx/pull/80
* Bump ua-parser-js from 0.7.31 to 0.7.33 in /website by dependabot in https://github.com/gbouvignies/ChemEx/pull/82
* Bump http-cache-semantics from 4.1.0 to 4.1.1 in /website by dependabot in https://github.com/gbouvignies/ChemEx/pull/83
* Bump sideway/formula from 3.0.0 to 3.0.1 in /website by dependabot in https://github.com/gbouvignies/ChemEx/pull/84
* Bump eta, docusaurus/core and docusaurus/preset-classic in /website by dependabot in https://github.com/gbouvignies/ChemEx/pull/85
* Bump future from 0.18.2 to 0.18.3 by dependabot in https://github.com/gbouvignies/ChemEx/pull/86
* Bump actions/checkout from 2 to 3 by dependabot in https://github.com/gbouvignies/ChemEx/pull/87
* Bump actions/setup-python from 3 to 4 by dependabot in https://github.com/gbouvignies/ChemEx/pull/88
* Bump eslint from 8.23.1 to 8.33.0 in /website by dependabot in https://github.com/gbouvignies/ChemEx/pull/90
* Bump hast-util-is-element from 1.1.0 to 2.1.3 in /website by dependabot in https://github.com/gbouvignies/ChemEx/pull/91
* Bump numpy from 1.24.1 to 1.24.2 by dependabot in https://github.com/gbouvignies/ChemEx/pull/94
* Bump eslint-plugin-react from 7.31.8 to 7.32.2 in /website by dependabot in https://github.com/gbouvignies/ChemEx/pull/92
* Bump docusaurus/eslint-plugin from 2.1.0 to 2.3.1 in /website by dependabot in https://github.com/gbouvignies/ChemEx/pull/93
* Bump cachetools from 5.2.0 to 5.3.0 by dependabot in https://github.com/gbouvignies/ChemEx/pull/95
* Bump matplotlib from 3.6.2 to 3.6.3 by dependabot in https://github.com/gbouvignies/ChemEx/pull/96
* Bump rich from 13.0.0 to 13.3.1 by dependabot in https://github.com/gbouvignies/ChemEx/pull/97
* Bump matplotlib from 3.6.3 to 3.7.0 by dependabot in https://github.com/gbouvignies/ChemEx/pull/98
* Bump pydantic from 1.10.4 to 1.10.5 by dependabot in https://github.com/gbouvignies/ChemEx/pull/101
* Bump scipy from 1.10.0 to 1.10.1 by dependabot in https://github.com/gbouvignies/ChemEx/pull/102
* Bump eslint from 8.33.0 to 8.34.0 in /website by dependabot in https://github.com/gbouvignies/ChemEx/pull/103
**Full Changelog**: https://github.com/gbouvignies/ChemEx/compare/v2022.2.0...v2022.3.0