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* :issue:`23`: Deprecate methods :meth:`pyvcf.VcfFrame.markmiss_ad/af/dp` and add new method :meth:`pyvcf.VcfFrame.markmiss`.
* Add new command :command:`vcf_filter`.
* Update methods :meth:`pycov.CovFrame.slice/plot_region`.
* :issue:`24`: Add new method :meth:`pyvcf.VcfFrame.drop_duplicates`.
* Update :meth:`pymaf.MafFrame.plot_snvcls` method to support various plotting modes.
* Rename ``horizontal`` argument of :meth:`pymaf.MafFrame.plot_varsum` method to ``flip``.