Glycogenius

Latest version: v1.1.41

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0.1.1beta

- Same isotopic peak will not get picked twice when tolerance is set too broad;
- Reduced memory usage during analysis by up to 10 times;
- Multithreaded the library generation algorithm, now should be significantly faster for large libraries;
- Small fix to better deal with corrupted MzML/MzXML files;
- Added a message on spectraviewer when you have a .gg file loaded but not the corresponding sample spectra file.

If GlycoGenius gets stuck, use the -console version and report the error you find, as well as what led to it.

0.1.0beta

- Generates .gg file after MS1 is done if MS2 is set to be performed and MS1 tracings have taken over 2 hours to complete, to avoid loss of data in case of crashes or lack of memory to finish the whole run;
- Options for forcing O-Glycans and GAGs compositions with proper restrictions to reduce search space efficiently;
- Reworked internal standard system, now supports chemical formula, glycans formula or mass, which then has its chemical formula derived from it, and now internal standard is properly deconvoluted and deisotopized, improving its quality;
- Added option to filter out glycans not found in at least a certain number of samples;
- Added percentage of glycans that are fucosylated, sialylated or both; Custom file name can now be set for .ggl and .gg file when generating library or starting an analysis;
- A lot of fixes.

If GlycoGenius gets stuck, use the -console version and report the error you find, as well as what led to it.

0.0.47beta

- Improved Gaussian fit to peaks;
- Other small fixes.

If GlycoGenius gets stuck, use the -console version and report the error you find, as well as what led to it.

0.0.46beta

- Small fix to rewind code to better support high sampling rate datafiles;
- Small fixes to GUI.

If GlycoGenius gets stuck, use the -console version and report the error you find, as well as what led to it.

0.0.45beta

- Added missing tooltips to sulfation and phosphorylation parameters;
- Fixed analysis info window not working.

If GlycoGenius gets stuck, use the -console version and report the error you find, as well as what led to it.

0.0.44beta

- Added support for Hexosamines and Uronic Acids;
- Added support for Sulfation and Phosphorylation in a per glycan basis;
- Highlighted isotopic peaks now show both the tolerance range and the picked peak;
- Added dropdown menu for reducing end tags;
- Small fixes all around.

If GlycoGenius gets stuck, use the -console version and report the error you find, as well as what led to it.

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