This release includes new features for multisample calling and some restructuring of the codebase to facilitate easier development in the future.
New features:
- Multisample calling for large input sets
Sniffles multiprocessing code has undergone a major rewrite with focus of enabling multisample calling for a large number of input files. To support this, the new optional dependency _psutil_ can be installed along with sniffles.
- Using alignments for multisample calling
Alignments can be used to improve separation of variants in multisample calling. This uses the new optional dependency _edlib_ and can be tweaked with the new argument `--combine-pctseq` defaulting to 0.7.
Required Python version has been updated to Python 3.10.