Mopepgen

Latest version: v1.4.5

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1.4.6rc3

- Added --skip-failed flag to callVariant, parseArriba, parserSTARFusion, parseFusionCatcher.

- Added tally table to parseREDITools, parseCIRCExplorer, and parseRMATS

1.4.6rc2

Fixed

- Fixed callVariant that variant bubble not identified correctly.

- Fixed parseVEP that failed records will now be skipped with --skip-failed. 902

- Fixed callVariant with variant bubble finding error starting from a out-bridge node.

- Fixed callVariant that peptide annotation not created correctly with SEC

Changed

- A check added when converting a genomic location to gene coordinate to ensure they overlap.

1.4.6rc1

Fixed

- Fix callVariant for a case that a bridge-out node was not identified correctly with a lot of framshift variants.

1.4.5

Fixed

- Variant peptide not split correclty if it is derived from fusion that the upstream and downstream are the same gene. 897

1.4.4

Fixed

- Fixed issue reported in 889 where variant bubbles alignment failed due to incorrect handling of in-bridge and out-bridge nodes with the same subgraph ID. The fix ensures that only in-bridge and out-bridge nodes connected to any of the nodes in the members of the variant bubble are considered.

- Fixed issue that `callVariant` fails on transcripts with SEC very close to the start codon.

- Fixed issue with extremely long run-time with complex alt splice events. 892

1.4.3

Fixed

- Fixed `VariantPeptideIdentifier` that ORF ID was added before variant IDs.

- Fixed `callVariant` that failed on small circRNA with a lot of variants at the step that creates the cleavage graph. 885

- Fixed `fuzzTest`. Parameters missing for `callVariant`.

Changed

- Changed variant IDs for circRNAs to use backsplicing site instead of listing all exons/introns. 878

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