Mopepgen

Latest version: v1.4.3

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0.8.0

Fixed

- Fixed issue that variants are not filtered correctly on `ThreeFrameCVG` (some variants are discarded or retained incorrectly). 488

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0.7.2

Changed

- Rolling back to not filtering candidate variant peptides that overlaps with canonical peptide pool at transcript level in `PeptideVariantGraph` because accessing the shared memory object is too slow (which could be optimized in the future).

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0.7.1

Changed

- `callVariant` optimized so the memory usage and run time is reduced to better handle hyper-mutated regions. 483

- Switched from [pathos](https://pathos.readthedocs.io/en/latest/index.html) to [ray](https://www.ray.io/) because the latter has better support for shared memory.

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0.7.0

Fixed

- Fixed the issue of long run time for transcripts with hypermutated regions by limiting number of additional variants per miscleavage (`--additional-variants-per-misc`). Closed 476 via 477

- Location was missing in variant labels output by `parseREDItools`. 478

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0.6.1

Fixed

- Deletion was mistreated as insertion when trying to convert to end-inclusion format. This only affects deletions that start on the third nucleotide of CDS. 468

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0.6.0

Fixed

- `callVariant` very slow on certain cases when the transcript is large. 464

- `callVariant` failed to find start codon for transcript with fusion being the first variant and the donor breakpoint is intronic. 465

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