Pyrodigal

Latest version: v3.6.3

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2.0.0

Added
- MMX implementation of the SIMD prefilter.
- Proper GFF headers and metadata section to GFF output.
- `Sequence.gc_frame_plot` method to compute the max GC frame profile from Python.
- `metagenomic_bin` property to `TrainingInfo` to support recovering the object corresponding to a pre-trained model.
- `meta` attribute to `Genes` to store whether genes were predicted in single or in meta mode.
- `pyrodigal.PRODIGAL_VERSION` constant storing the wrapped Prodigal version.
- `pyrodigal.MIN_SINGLE_GENOME` and `pyrodigal.IDEAL_SINGLE_GENOME` constants storing the minimum and recommended sequence sizes for training.

Changed
- Make all write methods of `Genes` objects require a ``sequence_id`` argument instead of using the internal sequence number.
- Rewrite SIMD prefilter using a generic template with C macros.
- Make `Mask` record coordinates in start-inclusive end-exclusive mode to follow Python conventions.
- Make connection scoring tests only score some randomly selected node pairs for faster runs.
- Rewrite tests to use `importlib.resources` for managing test data.

Removed
- `from_bytes` and `from_string` constructors of `Sequence` objects.

Fixed
- Duplicate extraction of start codons located on contig edges inside `Nodes._extract` ([21](https://github.com/althonos/pyrodigal/issues/21)).
- Pickling and unpickling of `TrainingInfo` objects corresponding to pre-trained models.
- Implementation of `calc_most_gc_frame` being inconsistent with the Prodigal implementation.
- Implementation of the maximum search in `score_connection_forward_start` not following the (weird?) behaviour from Prodigal ([21](https://github.com/althonos/pyrodigal/issues/21)).
- Gene identifier being used instead of the sequence identifier in the GFF output ([18](https://github.com/althonos/pyrodigal/issues/18)).
- Out of bound access to sequence data in `Sequence._shine_dalgarno_mm` and `Sequence._shine_dalgarno_exact`.

1.1.2

Changed
- Use the `vbicq` Arm intrinsic in the NEON implementation to combine `vandq` and `vmvnq`.

Fixed
- Prevent direct instantiation of `Node` and `Gene` objects from Python code.
- Configuration of platform-specific NEON flags in `setup.py` not being applied to the linker.

1.1.1

Fixed
- Some `cpu_features` source files not being included in source distribution.

1.1.0

Changed
- `OrfFinder.train` can now be given more than one sequence argument to train on contigs from an unclosed genome.
- Updated `cpu_features` to `v0.7.0` and added hardware detection of NEON features on Linux Aarch64 platforms.

1.0.2

Fixed
- Detection of Arm64 platform in `setup.py` ([16](https://github.com/althonos/pyrodigal/issues/16)).

1.0.1

Changed
- `pyrodigal.cli` now concatenates training sequences the same way as Prodigal does.

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